Welcome to GuideStar Research Resources

The case studies and whitepapers provide observations about how our services have helped clinical research programs become efficient and successful, and offer insights into navigating some of the more difficult aspects of clinical research.

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How one hospital is turning a 49% research department loss into a multi-million dollar program

A 400-bed hospital located in the Southeast had a history of conducting only cooperative group cancer trials. Cooperative group trials, while valuable to evaluate cancer therapies, pay very little, last for many years, and do not cover the expenses related to conducting the trials. To manage 50 cooperative group trials with more than 700 patients enrolled or in follow up, the hospital employed a staff of 4.5 FTEs and was operating at a sizable 49% financial loss.

View Cost Recovery Case Study


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Timeline Down, Profit Margin Up

A large, nationwide health system was very active in clinical research. However, because of the number of facilities and large geographic footprint, the corporate leaders did not have a clear picture of its financial status. In addition, requirements for corporate review of each study meant greatly extended pre-award processing timelines.

View Study Start Up Case Study

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Zero to $1.5 Million in Three Years – The Impact of Outsourcing Trial Budgeting

A hospital in the Midwest, which is part of a multi-facility health system, made the strategic commitment to offer clinical trial options to cancer patients in the communities it serves. The four medical oncologists on staff had some previous experience conducting trials, but were currently not participating in research.

View Trial Budgeting Case Study

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Existing Research Program – Realizing the Potential

In a fiercely competitive market in the south, a two-hospital health system strives to increase its market share through innovative strategies with a focus on strengthening medical staff relationships while building more depth into the existing physician specialties.

View Trial Operations Case Study

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Community Hospital Research Program – A Quick Start Approach

A 250-bed hospital in the Midwest recruited a cardiology group and cardiovascular surgeons to establish a heart and vascular service. These physicians had years of experience in research and were already conducting clinical trials. The recruiting hospital did not conduct research and had no infrastructure in place to handle clinical trial activities and processes.

View Quick Start Case Study

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Delivering Immediate Trial Opportunities

The oncology department of an east coast healthcare system was actively conducting clinical trials, however they were primarily low-funded co-operative group trials. Because leadership understood the financial impact research could have on the overall organization, it was decided to grow the trial pipeline by introducing industry sponsored research. Leadership recognized that external expertise could expedite achieving this goal.

View Site Pipeline Case Study

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Clinical Research Billing Minefield

A 480-bed Catholic not-for-profit hospital in the Midwest conducting diabetes research was contemplating expanding the program into additional specialties as a way to attract new physicians. Hospital leadership knew that before expanding its research program, they needed to ensure the foundation of the current research operation was strong, as well as gain a clear understanding of the research processes and function.

View Finance Case Study

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Decreasing CDA Turn-around Time by 81%

The cancer institute of an integrated healthcare system in the mid-Atlantic was active in clinical trials and acknowledged the importance research played in the overall organization. The institute was conducting low-funded co-operative group trials and, in an effort to realize increased revenue, research leadership wanted to introduce industry sponsored trials as part of the portfolio.

View CDA Turnaround Case Study

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Contract Research Organization: An Industry Analysis

U.S. pharmaceutical companies outsource research activities to contract research organizations (CROs) to increase their profit margins and better position themselves in the rapidly-changing healthcare environment. In this article, the authors explore the evolution of the CRO industry in the United States and worldwide, and discuss the benefits and pitfalls of CRO globalization in recent years.

View Contracts Whitepaper

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Know Your Numbers

Finding new efficiencies is a cornerstone of the new paradigm of clinical trial management. Pharmaceutical companies are shedding clinical trial oversight staff and formally partnering with CROs to assume those responsibilities. However, with that partnership comes the requirement for CROs to tighten belts and focus on being more efficient.

View E-Doc Management Systems Whitepaper

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A Business Approach to Integrating Clinical Research Sites in Mergers & Acquisitions

Mergers and acquisitions have become a progressively widespread strategy for achieving hospital growth and expansion. From hospitals to physician practices, the paradigm of merging for purposes of leveraging capital to strengthen competiveness continues to gain popularity.

View Mergers & Acquisitions Whitepaper